The Woman Who is the “Mother” of Us All

Scott November 1, 2012 11
Today I Found Out that all humans can be traced back to a single female known as Mitochondrial Eve.

This woman is thought to be the “mother” of all humans alive today. Seems like a big claim for scientists to make.  So how do they know this?  The simple explanation is that when an egg is fertilized by a sperm, the DNA from the father and mother join together in a process known as recombination. Certain DNA is only passed down from the mother or father.  All mitochondrial DNA (mtDNA) come exclusively from the mother, as an exact copy. Over time however, there will occur predictable mutations to mtDNA. Biologists can compare samples from individuals to determine how closely they are related- the fewer these predictable mutations, the closer the relationship.  The predictability of these mutations also allows biologists to estimate the time at which a certain mutation (i.e. ancestor) lived.  Beginning in 1987, several studies have been conducted that show all humans alive today have the same female ancestor and she lived approximately 200,000 years ago.

A more detailed explanation is as follows.  Mitochondria are a type of organelle found in almost all complex cells. They are known as the power plants of the cell because they supply an enzyme (more accurately a co-enzyme) known as adenosine triphosphate (ATP). This ATP is the source for the chemical energy needed by a cell to perform a wide range of functions. The DNA found within mitochondria have two benefits. They have 37 genes that rarely mutate, so they can be easily used as the model for an evolutionary clock, and these same genes have subsections that mutate in a predictable manor so biologists can use it as a reference for age.

Sperm have only a few mitochondria (and thus mitochondrial DNA) in their tails. They use them to power their quest to the egg. As the sperm enters the egg, only the chromosomes found in the head of the sperm are preserved and used in the recombination process to create new cells. This is because the rest of the sperm cell is broken down by enzymes within the egg. So the mitochondrial DNA in the tail is lost and the only type to survive is supplied by the mother.

As the human population grows from one generation to the next, women transfer this DNA evidence to their daughters. They, in turn, transfer it to their daughters. Should a woman have only a son, their mtDNA is lost, because it will never be passed to his children.

However, there have been a few rare cases in which mitochondrial DNA was found recombined from both parents. Some skeptics of the Mitochondrial Eve theory use this to cast doubt on the hypothesis. This opposition is somewhat dubious as those few cases occur in people who are typically far too biologically deficient  to have offspring. Thus, the prevailing assumption is that these unfortunate people have something seriously wrong with their DNA and the abnormal recombination of mtDNA will never get into the human population because of it.

Even though biologists have shown that all people are descended from one person, this does not mean that only one female was alive at that time. It simply means only one set of genes have been passed down from a single point in history. Most researchers agree that “Eve” was not the only women alive because the fossil record shows much older specimens. From “Java man” at about 800,000 years to “Lucy”, the earliest known remains which are approximately 1-4 million years old.

There are several theories about how just one set of genes could have survived. The most likely is a bottleneck of the human population that would set the stage for an evolutionary “lucky mother”. There have been several possible bottlenecks in history. One report, written in 1998, showed approximately 70,000 years ago humanity was down to around 15,000 people. It showed the reason behind the bottleneck was an ice age that lasted about a 1,000 years.

Other reasons bottlenecks could have happened are: an asteroid impact or volcanic eruption causing drastic climate change; a continuous, widespread plague; or any situation that caused male offspring to have a better chance of survival, leaving relatively few women around to pass on their genes. While no definitive proof exists that these occurred, most researchers believe a combination of one or all of these factors are behind why we all have a common ancestor.

Bonus Facts:

  • There is another type of genetic test that can trace all humans alive today back through their father’s ancestors. This uses what is known as the Y chromosome and shows that all people today can trace their lineage back to a single father known as “Y Chromosome Adam”.
  • Before you start throwing fuel on any religious fire, Y Adam lived at a completely different time then Eve. Approximately 60,000 -90,000 years ago. How can this be? Mitochondrial Eve is simply the most recent common ancestor of mtDNA. Y chromosomal Adam is the most recent common ancestor for Y DNA. They did not have to be a couple for both of their genes to be the source for all current humans. Think of it this way; you have two rivers flowing down two separate mountains joined at the bottom. We’ll call Mitochondrial Eve, “Mountain A”. We’ll call Y Adam, “Mountain B”. The rivers will be their respective genetic lines. As they cross paths at the bottom, the joined rivers create a bigger river that itself splits off into countless streams that is humanity today. Mountain A could be a thousand times older then mountain B. What matters is the point at which they crossed created all the streams (people) that exist down hill from that point. It would also not matter how many times Eve’s river split before it crossed with Adams, it only matters that they crossed and the only streams to survive came from both mountains.
  • There is an obvious disparity between the approximate age of Mitochondrial Eve and Y Chromosome Adam and the current fossil record. Because of this, there is a very heated debate between geneticists and paleoanthropologists about the true origins of human kind. The only thing they all seem to agree on is that all humans descended out of Africa at some point in history.
  • Since this article is filled with fairly complex knowledge crammed into a very short synopsis, I thought I’d leave you with a quick Adam and Eve Joke. What did Abel say to Adam and Eve? “It kills me how you’re raising Caine!”
  • OK, one more: What did Adam say to Eve? “I’ll be wearing the plants in this family!”  *crickets*

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11 Comments »

  1. Jake November 1, 2012 at 1:18 pm - Reply

    There is actually black people in africa whos genetics are also more similar to our ancestors. Which just adds to the out of africa theory.

  2. Joyce December 1, 2012 at 12:01 pm - Reply

    I don’t get the jokes at the end. Can someone explain the jokes?

    • okan December 25, 2013 at 6:18 pm - Reply

      lol normally you say you wear the pants in this family = being the boss in the family

      but they only had plants to cover their genetelia as you see in pictures so she says i’ll be wearing the plants , haha … yeah.

  3. Jake December 13, 2012 at 9:42 pm - Reply

    @joyce … adam and eve wore plants to cover up there genitalia.. So its a pun for “I’ll be wearing the pants in this relationship”

  4. random August 21, 2013 at 6:01 pm - Reply

    “The age for the Y-MRCA has been variously estimated as 188,000,[2] 270,000,[3] 306,000,[4] and 142,000[5] A paper published in March 2013 reported an older estimate of 338,000 years.[6] Then two simultaneous reports in August 2013 provide younger estimates, one suggested 180,000 to 200,000 years,[7] and another, based on the genome sequence of nine different populations, indicated the age between 120,000 and 156,000 years.[8]”

    http://en.wikipedia.org/wiki/Y_Chromosome_Adam

    Are you even trying anymore?

    • Daven Hiskey
      Daven Hiskey August 22, 2013 at 10:04 am - Reply

      @random: You are quoting papers from 2013. This article was written in early 2012 and published in late 2012.

  5. LOVEPAREEK August 22, 2013 at 6:23 am - Reply

    NICE WRITE SCOTT. KEEP THEM FLOWING.

  6. CrazedLeper November 28, 2013 at 11:16 am - Reply

    That one woman would not be Eve, she would be the wife of Noah. Everyone alive would have to have been related to her–but none of her predecessors or contemporaries would have survived her.

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